UFC 100 takes place at the Mandalay Bay Events Center in Las Vegas with a main event of UFC heavyweight champion Brock Lesnar vs. interim title-holder Frank Mir in a title-unification bout. However, two other main event-worthy fights take place on the pay-per-view card when UFC welterweight champion Georges St. Pierre takes on top contender Thiago Alves and "The Ultimate Fighter 9" coaches Michael Bisping and Dan Henderson clash in a middleweight bout with title implications.

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